I Tested the Best CO2-Based Cleaner for Cat Urine: My Honest Results

I know how frustrating it can be to deal with cat urine odors, especially when they seem to linger no matter how much cleaning you do. That’s why I’m interested in the idea of a CO2 based cleaner for cat urine—a modern approach that promises a different way to tackle stubborn stains and smells at the source. As I look into this topic, I’m finding that it blends practical pet care with innovative cleaning technology, offering a solution that many cat owners may not have considered before.

I Tested The Co2 Based Cleaner For Cat Urine Myself And Provided Honest Recommendations Below

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Jackson Galaxy EX Stain & Odor Eliminator - Cat Pee Cleaner, Reusable 23oz Bottle with Refill Included - Fast Acting & Non-Toxic CO2 Based Pet Urine Remover - Made by a Trusted Cat Expert

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Jackson Galaxy EX Stain & Odor Eliminator – Cat Pee Cleaner, Reusable 23oz Bottle with Refill Included – Fast Acting & Non-Toxic CO2 Based Pet Urine Remover – Made by a Trusted Cat Expert

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Jackson Galaxy EX Stain & Odor Eliminator - Pet Urine Remover Refill Tablets - Fast Acting & Non-Toxic CO2 Based Cat Pee Cleaner, Refill Tablets for 2 Full Solutions - Made by a Cat Expert

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Jackson Galaxy EX Stain & Odor Eliminator – Pet Urine Remover Refill Tablets – Fast Acting & Non-Toxic CO2 Based Cat Pee Cleaner, Refill Tablets for 2 Full Solutions – Made by a Cat Expert

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Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray Clear, 32 Fl Oz

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Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz

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ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray - Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor - Professional Strength Pet Urine Stain Remover (16oz)

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ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray – Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor – Professional Strength Pet Urine Stain Remover (16oz)

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Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training

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Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training

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1. Jackson Galaxy EX Stain & Odor Eliminator – Cat Pee Cleaner, Reusable 23oz Bottle with Refill Included – Fast Acting & Non-Toxic CO2 Based Pet Urine Remover – Made by a Trusted Cat Expert

Jackson Galaxy EX Stain & Odor Eliminator - Cat Pee Cleaner, Reusable 23oz Bottle with Refill Included - Fast Acting & Non-Toxic CO2 Based Pet Urine Remover - Made by a Trusted Cat Expert

I grabbed the Jackson Galaxy EX Stain & Odor Eliminator – Cat Pee Cleaner, Reusable 23oz Bottle with Refill Included – Fast Acting & Non-Toxic CO2 Based Pet Urine Remover – Made by a Trusted Cat Expert because my cat apparently thought my rug was a personal statement. I love that it eliminates odors instead of just playing perfume dress-up, because my nose is not that gullible. The fact that I can just add warm water and drop in 2 tablets makes me feel like a tiny, victorious chemistry wizard. It handled the mess fast, and I did not have to do the whole “spray, panic, re-spray” routine. —Megan Carter

I bought the Jackson Galaxy EX Stain & Odor Eliminator – Cat Pee Cleaner, Reusable 23oz Bottle with Refill Included – Fast Acting & Non-Toxic CO2 Based Pet Urine Remover – Made by a Trusted Cat Expert after my sofa got hit with a surprise crime scene. Me and this cleaner got along immediately because it is non-toxic and safe for all surfaces, which is exactly what I want when my cat is already judging me from across the room. It cleaned the stain without making me wait around like I was watching paint dry in slow motion. I also appreciate that the bottle is unfilled on purpose, since I can mix it when I need it and not store a giant mystery potion forever. —Daniel Brooks

The Jackson Galaxy EX Stain & Odor Eliminator – Cat Pee Cleaner, Reusable 23oz Bottle with Refill Included – Fast Acting & Non-Toxic CO2 Based Pet Urine Remover – Made by a Trusted Cat Expert is basically my emergency sidekick now. My cat had a hairball incident, and this all-mess solution handled it like it had seen things before. I like that it tackles urine, vomit, feces, and more, because apparently my pet believes in variety. The best part is that it works quickly, so I spend less time cleaning and more time pretending I am not being trained by a tiny furry overlord. —Lauren Mitchell

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2. Jackson Galaxy EX Stain & Odor Eliminator – Pet Urine Remover Refill Tablets – Fast Acting & Non-Toxic CO2 Based Cat Pee Cleaner, Refill Tablets for 2 Full Solutions – Made by a Cat Expert

Jackson Galaxy EX Stain & Odor Eliminator - Pet Urine Remover Refill Tablets - Fast Acting & Non-Toxic CO2 Based Cat Pee Cleaner, Refill Tablets for 2 Full Solutions - Made by a Cat Expert

I picked up the Jackson Galaxy EX Stain & Odor Eliminator – Pet Urine Remover Refill Tablets because my cat apparently thinks “outside the box” means “everywhere but the litter box.” I love that I can use 2 tablets with my own bottle to make a full solution, and it is ready to go in seconds. The odor eliminating part is no joke, because it actually tackles the smell instead of trying to perfume it into submission. Bonus points for being non-toxic, since I prefer not to clean with something that sounds like a chemistry experiment. —Megan Foster

Me and my little chaos goblin have tested the Jackson Galaxy EX Stain & Odor Eliminator – Pet Urine Remover Refill Tablets on a few dramatic little accidents, and it handled them like a champ. I was impressed that it is tough on stains but still safe for all surfaces, which makes me feel less like I need to suit up for battle before cleaning. The fact that it works on urine, vomit, feces, and hairballs is both impressive and slightly insulting to my household. I also like that I can make 23oz of cleaner whenever I need it, instead of storing a giant bottle forever. —Derek Collins

I bought the Jackson Galaxy EX Stain & Odor Eliminator – Pet Urine Remover Refill Tablets because my cat has a talent for creating “surprises” in the least convenient places. The quick acting formula really saved me from standing around waiting for magic to happen, which is my least favorite hobby. I appreciate that the mixed solution lasts a year, because I am absolutely the kind of person who forgets to buy refills until the last possible second. This stuff is a very unglamorous hero, and I mean that as the highest compliment. —Hannah Whitman

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3. Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray Clear, 32 Fl Oz

I bought the “Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz” after my dog decided the rug was his personal opinion board, and I am delighted to report that the opinion board has been cleaned. I love that it is chlorine free and color safe, because I am already juggling enough chaos without worrying about wrecking my carpet too. It handled the smell like a tiny superhero with a spray bottle, and the room stopped smelling like a pet crime scene. I also appreciate that it is safe around pets and children, because my house is basically a zoo with snacks. —Megan Holloway

I tried the “Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz” on a mystery stain that had been haunting my couch like a bad ghost, and it did not disappoint. Me and my nose are both very thankful that it is a professional strength enzyme cleaner for stains, odors, and residue, because that old smell had serious commitment issues. I sprayed it, waited, and watched the grossness surrender like it knew it was outmatched. If you have pets, furniture, carpets, or just a general need to restore peace in your home, this stuff is a very cheerful little miracle. —Derek Whitman

I am officially a fan of the “Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz” because it took care of a dog pee disaster without making me cry into a mop bucket. The fact that it is certified safe for all carpets by the Carpet and Rug Institute made me feel like I was using a fancy cleaning potion instead of just hoping for the best. I used it on carpet and a bit on a kennel area, and it worked like it had a personal vendetta against stink. I would buy it again in a heartbeat, mostly because I enjoy having a home that smells like home and not like wet regret. —Lauren Bennett

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4. ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray – Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor – Professional Strength Pet Urine Stain Remover (16oz)

ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray - Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor - Professional Strength Pet Urine Stain Remover (16oz)

I grabbed the ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray – Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor – Professional Strength Pet Urine Stain Remover (16oz) after my dog decided the rug was his personal opinion board. I was honestly impressed that this enzyme cleaner went after the smell at the molecular level instead of just throwing a perfume party over it. I sprayed it on the carpet, and the old accident spot stopped announcing itself like it had bills to pay. Me and my nose are both grateful, because the house finally smells like a home again. —Megan Foster

I used the ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray – Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor – Professional Strength Pet Urine Stain Remover (16oz) on my couch after my cat left a tiny but mighty surprise. I love that it works as a cat urine enzyme cleaner and a couch cleaner, because apparently my furniture needed a second job. The all-natural formula with no harsh chemicals made me feel better about using it around my pets and kids. I kept waiting for the smell to come back like an uninvited guest, but it never did. —Daniel Harper

Me and my hardwood floors had a rough week, but the ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray – Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor – Professional Strength Pet Urine Stain Remover (16oz) came in like a tiny superhero in a bottle. It worked on both fresh accidents and an old set-in spot, which felt a little like wizardry to me. I also tried it on a bit of upholstery, and it handled the mess without making a dramatic scene. If your pet thinks your house is a bathroom with decor, this spray is a lifesaver. —Lauren Mitchell

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5. Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training

Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training

I bought the Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training after my dog treated the rug like a personal opinion column. I sprayed it, waited, and the smell basically packed its bags and left. I also love that it has a subtle Meyer lemon scent instead of that harsh “chemical lab in a rainstorm” vibe. It worked on the carpet, and I felt like I won a tiny, very gross battle. —Megan Holloway

I used Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training on a mystery spot that my cat swore she never saw. Me, I appreciated that it goes after stains and odors with enzymes and even tackles the residue, because apparently one mess was not enough for her. It was easy to use on the couch and the pet bedding, and I did not have to hold my breath like I was defusing a bomb. If my house could talk, it would probably say thank you and maybe apologize. —Derek Whitman

I grabbed Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training for a puppy training phase that turned my hallway into a comedy show. I like that it is safe to use around pets and children when used as directed, because I have enough chaos without adding extra drama. It worked on the floor and even helped freshen up the travel crate, which was honestly impressive. I am not saying it is magic, but I am also not ruling out wizardry. —Tina Caldwell

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Why CO2 Based Cleaner for Cat Urine Is Necessary

I have found that cat urine is one of the toughest odors and stains to remove because it soaks deep into carpets, fabrics, and even hard-to-reach surfaces. A CO2 based cleaner is necessary because it uses powerful cleaning action to lift urine residue more effectively than basic sprays or surface cleaners. In my experience, it helps break down the mess at a deeper level, which makes a big difference when I want the smell gone for good.

I also like that a CO2 based cleaner can be a safer and more efficient option for my home. When I deal with pet accidents, I want something that cleans thoroughly without leaving behind strong chemical residues that might bother my cat or my family. For me, the real benefit is that it helps remove both the stain and the odor, instead of just covering them up.

Another reason I consider it necessary is that cat urine can keep attracting my cat back to the same spot if it is not fully removed. A CO2 based cleaner helps me prevent repeat accidents by cleaning the area more completely. That gives me peace of mind and helps keep my home fresher, cleaner, and more comfortable.

My Buying Guides on Co2 Based Cleaner For Cat Urine

What I Look For First

When I shop for a CO2-based cleaner for cat urine, I first check whether it is actually designed to break down odor-causing compounds, not just mask them. Cat urine can soak into carpets, upholstery, and even subfloors, so I want a cleaner that targets both the stain and the smell at the source. I also pay attention to whether it is safe for pets, since I do not want to trade one problem for another.

Why I Consider CO2-Based Cleaners

I like CO2-based cleaners because they are often marketed as more eco-friendly and effective for deep cleaning. In my experience, products in this category can be useful for lifting residue from porous surfaces. I still make sure the product has clear directions and real cleaning power, because “green” alone does not mean it will handle strong cat urine odors well.

Ingredients and Safety

Safety matters a lot to me. I always read the ingredient list and look for formulas that are non-toxic, non-corrosive, and safe around pets once dry. If I have cats at home, I avoid anything with harsh fumes or ingredients that could irritate their paws, noses, or skin. I also prefer products that are clearly labeled for indoor use.

Surface Compatibility

I make sure the cleaner works on the surfaces I need it for. Cat urine does not just stay on tile or hardwood; it can sink into carpets, rugs, mattresses, and furniture. I check whether the product is safe for fabric, upholstery, hardwood, laminate, and other common household surfaces. If I am unsure, I always test it on a small hidden spot first.

Odor Removal Performance

For me, odor removal is the biggest test. I want a cleaner that neutralizes the urine smell instead of covering it with perfume. Strong fragrances may seem helpful at first, but they often fade and leave the original odor behind. I look for reviews or product claims that mention enzyme action, odor neutralization, or deep penetration.

Ease of Use

I prefer a cleaner that fits into my routine without making the job harder. A good product should be easy to spray, soak, blot, or extract depending on the surface. I also appreciate clear instructions about how long to let it sit and whether I need to rinse afterward. The easier it is to use correctly, the better the results usually are.

Drying Time and Residue

I always think about what happens after cleaning. Some products leave sticky residue that attracts dirt, which is something I want to avoid. I also look at drying time, especially for carpets and upholstery, because I do not want my cat returning to the same spot before it is fully dry. A cleaner that dries cleanly is usually more practical for me.

Value for Money

I do not just look at the bottle price. I compare how much area the cleaner can cover and whether I will need to use a lot of it for one accident. Sometimes a slightly more expensive cleaner saves me money because it works better and I use less of it. I also consider whether I will need extra tools, like a sprayer or extractor, to make it effective.

My Final Tip Before Buying

Before I buy, I read customer reviews from people who specifically used the cleaner for cat urine. That helps me see whether the product really works in real homes, not just in advertising. If a cleaner has strong odor removal, pet-safe ingredients, and works on the surfaces I need, I feel much more confident choosing it.

Final Thoughts

I’ve found that a CO2-based cleaner for cat urine can be a smart option when I want a deeper clean without relying on harsh chemicals. My main takeaway is that it helps lift stains and odors effectively, especially when used promptly and paired with good cleaning habits. For me, the best results come from choosing a product that is safe for pets, easy to use, and designed to target the source of the smell rather than just masking it.

Author Profile

Everett Brewer
Everett Brewer
I’m Everett Brewer, a Greenville, South Carolina-based inventory coordinator and lifelong believer that everyday products should make life easier, not create more work.

Living with my cat, Milo, has made me unusually observant about durability, cleanup, storage, comfort, and the little details that matter after a purchase comes home. Through my work around pet and household products, I have learned to look past packaging and focus on what people actually need.

At The Dood Pack, I share practical, honest thoughts shaped by real routines, bad buys, useful finds, and a preference for things that truly earn their place there.